Dengue virus detection kit can be used for screening and assististing in the diagnosis of early dengue infection from whole blood (venous or fingertip blood), serum or plasma sample. The test is supposed to be used for in vitro qualitative detection of non-structural protein 1 (NS1) of dengue virus. This protein is secreted into the blood during a dengue infection.

Dengue fever is a mosquito-borne viral infection caused by the dengue virus (DENV), which belongs to the Flavivirus family. It is an acute infectious disease transmitted by Aedes aegypti and Aedes albopictus, and is more common in tropical and subtropical regions. The clinical types can be divided into three types: dengue fever, dengue hemorrhagic fever and dengue shock syndrome. The test only needs to use a disposable plastic straw to vertically drop 1 drop of fingertip blood sample or serum, plasma, whole blood sample into the sample well, and then drop 2 drops of sample diluent to start timing. Read the result in 10 minutes, the result is valid within 30 minutes.

Symptoms of Dengue Fever. Symptoms typically appear 4–10 days after being bitten by an infected mosquito and can range from mild to severe. They may include:

• Sudden high fever (40°C/104°F)
• Severe headache
• Pain behind the eyes (retro-orbital pain)
• Muscle and joint pain ("breakbone fever")
• Skin rash (may appear 2–5 days after fever starts)
• Nausea and vomiting
• Fatigue and weakness

There is no specific antiviral treatment for dengue. Special focus is put on rest and hydration during infection period. Severe cases may require intravenous fluids, blood transfusions, and close monitoring for complications.

Early diagnosis and timely treatment are crucial for managing dengue infection. There is a global demand for affordable, sensitive, and easy-to-use point-of-care diagnostic tools with a long shelf life for quick detection. Rapid diagnostic tests (RDTs) are cost-effective, fast, and simple to use. The Synthgene Dengue Virus Detection Kit meets these needs, making it ideal for clinical settings or home testing.